Gene interactions and pathways from curated databases and text-mining

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IL21 — MMP24

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Monteleone et al., Gut 2006 (Colitis, Ulcerative...) : To investigate whether IL21 controls MMP production by intestinal fibroblasts ... IL21 enhances fibroblast production of MMP-1, MMP-2 , MMP-3 and MMP-9, but not tissue inhibitors of MMP-1 and MMP-2 ... IL21 enhances MMP secretion without affecting gene transcription and protein synthesis ... These results suggest that fibroblasts are a potential target of IL21 in the gut and that IL21 controls MMP secretion by fibroblasts
Caruso et al., J Immunol 2007 (Gastritis...) : In this study, we have examined the role of the T cell cytokine IL-21 in Hp-infected gastric mucosa and evaluated whether IL-21 regulates MMP production by gastric epithelial cells