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HRAS — IL3

Pathways - manually collected, often from reviews:

• Reactome Reaction: IL3 → HRAS (reaction) Chardin et al., Science 1993

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: IL3 — HRAS (in vitro) Deng et al., Proc Natl Acad Sci U S A 2000*

Text-mined interactions from Literome

Duronio et al., Proc Natl Acad Sci U S A 1992 : We demonstrate here that ligand induced activation of the interleukin (IL)-2, IL-3 , IL-5, and granulocyte-macrophage colony stimulating factor receptors resulted in activation of p21ras in various hemopoietic cell lines
Izquierdo et al., Eur J Immunol 1992 : Our data show that IL-3 is able to activate p21ras in the parental 32D cells and both IL-2 and IL-3 can stimulate p21ras in the IL-2R expressing beta 53 clone of 32D
Neumann et al., Eur J Immunol 1996 (Multiple Myeloma) : Like many other cytokines and growth factors, interleukin-6 (IL-6) activates p21ras
Hirsch et al., Growth Factors 1996 : Autocrine interleukin-3 (IL-3) expression of v-H-ras transformed mast cell tumors involves either IL-3 mRNA stabilization ( class-I tumors ) or enhanced IL-3 transcription ( class-II tumors )