Gene interactions and pathways from curated databases and text-mining

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IL3 — LTB

Text-mined interactions from Literome

Rola-Pleszczynski et al., Union Med Can 1989 : In particular, LTB4 can induce suppressor cells, activate the synthesis and production of lymphokines such as interleukin 2 or interferon-gamma, stimulate the production of interleukin 1 by monocytes or macrophages, and activate cytotoxic cells against virus infected or tumor target cells
Matsumoto et al., Prostaglandins Leukot Essent Fatty Acids 1995 (Leukemia, Basophilic, Acute) : IL-3 and IL-5 enhance the production of LTB4 stimulated by calcium ionophore in rat basophilic leukemia cells ... These results suggest that IL-3 and IL-5 increase the production of LTB4 by priming the activity of phospholipase A2(PLA2) without inducing enzymes in the arachidonate 5-lipoxygenase pathway