Gene interactions and pathways from curated databases and text-mining

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IL33 — IRF3

Text-mined interactions from Literome

Polumuri et al., J Immunol 2012 : Treatment of primary murine macrophages with a panel of TLR ( e.g., TLR2, TLR3, TLR4, and TLR9 ) agonists and non-TLR ( e.g., MDA5, RIG-I ) agonists revealed a pattern of gene and protein expression consistent with a role for IFN regulatory factor-3 (IRF-3) in the expression of IL-33
Tang et al., PloS one 2013 : The adjuvant effect was directly dependent on the IRF3 mediated production of type-I-interferon, but not IL-33
Ysebrant de Lendonck et al., Proc Natl Acad Sci U S A 2013 : Interferon regulatory factor 3 controls interleukin-17 expression in CD8 T lymphocytes