Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Ohtani et al., Blood 2008 (Leishmaniasis, Cutaneous) : Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide induced interleukin-12 production in dendritic cells
Salmond et al., J Allergy Clin Immunol 2012 (Pneumonia) : Our goal was to investigate a role for mammalian target of rapamycin (mTOR) signaling in the activation of T ( H ) 2 and ILC responses and the induction of airway inflammation by IL-33 ... We biochemically determined the effect of IL-33 on mTOR activation in T ( H ) 2 cells and ILCs and examined the effect of this signaling pathway in vivo using a murine model of IL-33 induced lung inflammation ... We found that IL-33 induces mTOR activation through p110d phosphoinositide 3-kinase and that blockade of the mTOR pathway inhibited IL-33 induced IL-5 and IL-13 production by T ( H ) 2 cells and ILCs