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IL7 — SOAT1
Text-mined interactions from Literome
Fleming et al., J Immunol 2004
:
Cell lines derived from CD45-deficient animals experience prolonged
JAK/STAT activation in
response to
IL-7 stimulation, and constitutively elevated levels of phosphorylated src kinases
Barata et al., Leukemia & lymphoma 2005
(Leukemia-Lymphoma, Adult T-Cell) :
IL-7 induces the activation of
Jak/STAT , MEK/Erk and PI3K/Akt signaling pathways in T-ALL cells
Sharfe et al., Blood 1995
:
We describe here a novel function of the Jak kinases, because Jak kinase activity is not only required for
Stat activation but also for P13 kinase
response to
IL-7 in human T cells
Seidel et al., Proc Natl Acad Sci U S A 1995
(Carcinoma, Hepatocellular...) :
We have systematically examined the effects of the spacing between the TT and AA core half sites on the binding of the
STAT complexes
activated by IFN-gamma,
interleukin (IL) 6, granulocyte-macrophage colony stimulating factor, and IL-4
van der Plas et al., Leukemia 1996
(Burkitt Lymphoma...) :
IL-7 also
induced STAT/DNA binding in BCP-ALL cases that failed to proliferate in response to IL-7, suggesting that the ability of IL-7R to activate the JAK/STAT pathway per se is not sufficient for proliferation induction