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INS — SLPI
Text-mined interactions from Literome
Rubinacci et al., Minerva Endocrinol 1991
(Diabetes Mellitus) :
The results indicate that
insulin significantly ( p less than 0.012 )
increases ALP by a mean value of 48 % ( from 5.4 % to 215 % ) over matched controls
Yuan et al., PloS one 2011
(MAP Kinase Signaling System) :
Our experiments demonstrated that
insulin could
promote alkaline phosphatase (ALP) activity, osteocalcin expression and the formation of mineralized nodules in CVSMCs. Suppression of receptor activator of nuclear factor ?B ligand ( RANKL ) with small interfering RNA ( siRNA ) abolished the insulin induced ALP activity
Ju Ha et al., J Recept Signal Transduct Res 2013
(MAP Kinase Signaling System) :
In the present study, we explored to determine if insulin receptor could associate with syndecan-1 in
response to
insulin and such association could lead to the activation of subsequent ERK I/II and
alkaline phosphatase (ALP) in osteoblast cells ... Pretreatment of synstatin also inhibited the
insulin stimulated
ALP activity