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IRF6 — RHOA

Text-mined interactions from Literome

Schmeck et al., Inflammation 2003 : Therefore, RhoA/Rac1/Cdc42 contribute to NF-kappaB dependent LPS- and TNFalpha induced expression of PGHS-2 in EC but had no effect on the activity of expressed COX-1 and COX-2
Pomorski et al., Cell Motil Cytoskeleton 2004 : LPS suppressed Rho A activity and either this agent or C3 transferase elevated intracellular free calcium, stabilized transcripts, and, in tandem, inhibited cell migration by preventing tail retraction, a prerequisite for cell translocation
Kamon et al., EMBO J 2006 : LPS increased the activity of RhoB, but not of RhoA , Cdc42, or Rac1/2 in a manor dependent on LPS-TRIF- but not LPS-Myd88 signaling
Shimizu et al., Mol Hum Reprod 2007 : Pull-down assays showed that LPS activated RhoA , but IL-1beta caused only a lower level of activation
Polk et al., Am J Physiol Cell Physiol 2007 (Nephritis) : Conversely, constitutive expression of RhoA prevented NF-kappaB activation by LPS , and this effect was reversed by cotransfection with MEKK1-KD
Soliman et al., Cardiovasc Res 2008 (Diabetes Mellitus, Experimental...) : Both SNP and LPS increased RhoA expression in non-diabetic cardiomyocytes
Toguchi et al., Neurochem Int 2009 : We also provide evidence that LPS markedly upregulated Plexin-B1 expression in microglia and Sema4D/CD100 stimulated RhoA-activation in LPS activated microglia
Mambetsariev et al., Arterioscler Thromb Vasc Biol 2010 (Acute Lung Injury...) : Silencing protease activated receptor 1 and 3, RhoA , or Rho kinase expression attenuated LPS- , LMW-HA-, and HABP2 mediated EC barrier disruption
He et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2010 : LPS activated RhoA and NF-?B at 0.5 h ... LPS induces the disruption of F-actin cytoskeleton and brain microvascular endothelial barrier integrity, in part, through RhoA and NF-?B activation
Yao et al., Biochim Biophys Acta 2011 (Lung Injury) : LPS activated both Rac1 and Rac2, but not CDC42 or RhoA activities in lungs, and specific inhibition of Rac activities by NSC23766 effectively alleviated LPS induced injury