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CREB5 — IRS2

Text-mined interactions from Literome

Jhala et al., Genes Dev 2003 (Diabetes Mellitus...) : cAMP promotes pancreatic beta-cell survival via CREB mediated induction of IRS2
Costes et al., Diabetes 2006 : cAMP-responsive element binding protein ( CREB ) is required for beta-cell survival by regulating expression of crucial genes such as bcl-2 and IRS-2
Liu et al., PloS one 2012 (Diabetes Mellitus, Type 2) : This study investigated whether CaMK4 is also a potential target to increase ß-cell mass through CREB mediated IRS-2 expression, by quantifying mouse MIN6 ß-cell proliferation and apoptosis following IRS-2 knockdown, CaMKs inhibition and alterations in CaMK4 and CREB expression