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CTNNB1 — ISL1

Pathways - manually collected, often from reviews:

• WikiPathways Heart Development: CTNNB1 → ISL1 (inhibition) Kwon et al., Nat Cell Biol 2009*

Text-mined interactions from Literome

Lin et al., Proc Natl Acad Sci U S A 2007 : Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis ... Here we demonstrate that beta-catenin is required for Isl1 expression in cardiac progenitors, directly regulating the Isl1 promoter
Kwon et al., Nat Cell Biol 2009 : Notch1 positively, and beta-catenin negatively, regulated expression of the cardiac transcription factors, Isl1 , Myocd and Smyd1