Gene interactions and pathways from curated databases and text-mining

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ITGA5 — TGFB1

Text-mined interactions from Literome

Knight et al., Am J Pathol 2002 (Hyperplasia...) : The epithelial integrin alpha(v)beta ( 6 ) mediates local activation of TGF-beta(1) in the lung and beta ( 6 ) ( -/- ) mice exhibit exaggerated pulmonary inflammation, but their response to inflammatory stimuli in the gut has not been investigated
Zhou et al., J Biol Chem 2010 : These data suggest that Thy-1-integrin alpha(v)beta(5) interactions inhibit contraction induced latent TGF-beta1 activation, presumably by blocking the binding of extracellular matrix bound latent TGF-beta1 with integrin alpha(v)beta(5)
Wang et al., J Biol Chem 1995 (Colonic Neoplasms) : Autocrine TGF-beta 1 had no effect on the transcription of integrin alpha 5 and beta 1 subunits, indicating that autocrine TGF-beta 1 may regulate integrin alpha 5 beta 1 expression at the post-transcriptional level
Collo et al., J Cell Sci 1999 : We have investigated the effect of wound induced two-dimensional migration, basic fibroblast growth factor (bFGF), transforming growth factor-beta1 ( TGF-beta1 ) and leukemia inhibitory factor (LIF) on expression of the alpha5beta1 integrin in endothelial cells ... We have investigated the effect of wound induced two-dimensional migration, basic fibroblast growth factor (bFGF), transforming growth factor-beta1 ( TGF-beta1 ) and leukemia inhibitory factor (LIF) on expression of the alpha5beta1 integrin in endothelial cells