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IL7 — JAK2

Text-mined interactions from Literome

Fleming et al., J Immunol 2004 : Cell lines derived from CD45-deficient animals experience prolonged JAK/STAT activation in response to IL-7 stimulation, and constitutively elevated levels of phosphorylated src kinases
To et al., Br J Cancer 2004 (Cell Transformation, Neoplastic...) : The interleukin mediated Janus kinase ( JAK ) /STAT pathway plays a crucial role in carcinogenesis
Barata et al., Leukemia & lymphoma 2005 (Leukemia-Lymphoma, Adult T-Cell) : IL-7 induces the activation of Jak/STAT , MEK/Erk and PI3K/Akt signaling pathways in T-ALL cells
Sharfe et al., Blood 1995 : Specific inhibition of IL-7 induced Jak kinase activity ablates p85 tyrosine phosphorylation, subsequent P13 kinase activation, and, ultimately, proliferation