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JAK2 — TGFB1
Text-mined interactions from Literome
Sudarshan et al., J Immunol 1999
:
Similarly, but in contrast to previous reports, we found that
TGF-beta1 did not
inhibit IL-2 induced phosphorylation of JAK1,
JAK3 , and STAT5A
Nagineni et al., J Cell Physiol 2007
:
JAK inhibitor selectively inhibited IFN-gamma
induced TGF-beta1 secretion and mRNA levels while reversing the inhibitory effects of IFN-gamma on TGF-beta2
Park et al., Mol Immunol 2007
(MAP Kinase Signaling System) :
We have shown previously that
TGF-beta1 inhibits Th1 development by inhibiting IFN-gamma 's induction of T-bet and other Th1 differentiation genes, and that TGF-beta1
inhibits receptor-proximal
IFN-gamma-Jak-Stat signaling responses
Zhang et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2007
:
To evaluate the
effect of
JAK/STAT signaling pathway activation on the transdifferentiation and secretion of
transforming growth factor-beta1 ( TGF-beta1 ) induced by high glucose in renal proximal tubular epithelial cells
Yu et al., Int J Biochem Cell Biol 2008
:
SOCS 3 and PPAR-gamma ligands
inhibit the expression of IL-6 and
TGF-beta1 by regulating
JAK2/STAT3 signaling in pancreas