Gene interactions and pathways from curated databases and text-mining

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JAK2 — TGFB1

Text-mined interactions from Literome

Sudarshan et al., J Immunol 1999 : Similarly, but in contrast to previous reports, we found that TGF-beta1 did not inhibit IL-2 induced phosphorylation of JAK1, JAK3 , and STAT5A
Nagineni et al., J Cell Physiol 2007 : JAK inhibitor selectively inhibited IFN-gamma induced TGF-beta1 secretion and mRNA levels while reversing the inhibitory effects of IFN-gamma on TGF-beta2
Park et al., Mol Immunol 2007 (MAP Kinase Signaling System) : We have shown previously that TGF-beta1 inhibits Th1 development by inhibiting IFN-gamma 's induction of T-bet and other Th1 differentiation genes, and that TGF-beta1 inhibits receptor-proximal IFN-gamma-Jak-Stat signaling responses
Zhang et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2007 : To evaluate the effect of JAK/STAT signaling pathway activation on the transdifferentiation and secretion of transforming growth factor-beta1 ( TGF-beta1 ) induced by high glucose in renal proximal tubular epithelial cells
Yu et al., Int J Biochem Cell Biol 2008 : SOCS 3 and PPAR-gamma ligands inhibit the expression of IL-6 and TGF-beta1 by regulating JAK2/STAT3 signaling in pancreas