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ANG — JUN

Text-mined interactions from Literome

Kim et al., Pharmacol Rev 2000 (Cardiovascular Diseases...) : Furthermore, in vivo recent evidence suggest that the activation of mitogen activated protein kinases and activator protein-1 by Ang II may play the key role in cardiovascular and renal diseases
Murasawa et al., J Biol Chem 2000 (Calcium Signaling) : These results suggest that 1 ) in cardiac fibroblasts activation of JNK and c-Jun by Ang II is initiated by Pyk2 dependent signalings but not by downstream signals of EGF-R or Ras, 2 ) Rac1 but not Cdc42 is required for JNK activation by Ang II upstream of MEKK1, and 3 ) ATF-2/c-Jun binding to the activator protein-1 sequence at -190 plays a key role for induction of c-Jun gene by Ang II
Chen et al., Blood 2004 : Angiotensin II (Ang II) stimulation increased c-Fos, c-Jun , and Sp1 binding to the MRE by 100-, 4.9-, and 1.9-fold, respectively, and these responses were inhibited by PD98059 and AT1 receptor antagonist candesartan
Zhang et al., American journal of physiology. Renal physiology 2005 : Angiotensin II (ANG II) has been shown to activate c-Jun NH2-terminal kinase (JNK) in cultured mesangial cells, but the functional implication of this phenomenon remains to be determined, largely due to the lack of an effective approach to block JNK
Blume et al., Am J Physiol Regul Integr Comp Physiol 2005 : Similar to ANG II, ANG III induced the expression of c-Fos, c-Jun , and Krox-24 in four brain regions, subfornical organ, median preoptic area, paraventricular nucleus, and supraoptic nucleus of the hypothalamus, with the same efficacy
Li et al., Regul Pept 2007 (Liver Cirrhosis, Experimental) : However, the signal transduction mechanism underlying effects of Angiotensin II (Ang II) and Aldosterone ( Aldo ) on Nuclear Factor-kappaB (NF-kappaB) and active protein-1 (AP-1) pathway in hepatic fibrogenesis remains to be fully elucidated
Hattori et al., Diabetes 2007 : gAd also activated AP-1 and enhanced angiotensin II (Ang II) induced AP-1 activity
Nie et al., Mol Immunol 2009 : Both Ang- ( 1-7 ) and Ang II had no effect on p38 and c-Jun N-terminal kinase (JNK) phosphorylation
Chen et al., Neurosci Res 2009 (MAP Kinase Signaling System) : Downstream of beta1-integrin, Ang1 stimulation led to a approximately 2.6 fold increase in focal adhesion kinase ( FAK ) phosphorylation and no change in the activation of mitogen activated protein kinase ( MAPK ) nor c-Jun N-terminal kinase (JNK)
Naftilan et al., Mol Cell Biol 1990 : This study demonstrated that Ang II also activated c-jun and, in addition, could activate the AP-1 enhancer element