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LRP1 — MMP2

Text-mined interactions from Literome

Yang et al., J Biol Chem 2001 : Addition of heparin, which competes for the binding of TSP2 to LRP coreceptor proteoglycans, inhibited adhesion of control but not TSP2-null cells, and a blocking antibody to LRP as well as the LRP inhibitor, receptor associated protein, also inhibited adhesion and increased MMP2 levels only in control fibroblasts
Emonard et al., Biochimie 2005 : Regulation of matrix metalloproteinase ( MMP ) activity by the low-density lipoprotein receptor related protein ( LRP )
Desrosiers et al., Pediatr Blood Cancer 2006 (Kidney Neoplasms...) : The proteolytic processing of MT1-MMP , a functional regulator of LRP , also correlated with the WT invasive phenotype
Song et al., Cancer Res 2009 (Glioblastoma...) : Here, we reveal a novel mechanism by which LRP1 induces the expression of matrix metalloproteinase 2 (MMP2) and MMP9 and thereby promotes the migration and invasion of human glioblastoma U87 cells
Poon et al., Mol Endocrinol 2011 (Neoplasm Invasiveness...) : Overexpressing LRP in these cells increases MMP-2 production specifically, while a laminin binding deficient LRP does not