Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Huang et al., J Biol Chem 2004 (Rhabdomyosarcoma) : Inhibition of mammalian target of rapamycin activates apoptosis signal regulating kinase 1 signaling by suppressing protein phosphatase 5 activity
Zhan et al., Mol Cell Biol 2007 : Activation of apoptosis signal regulating kinase 1 ( ASK1 ) induced by inhibition of mTOR signaling leads to sustained phospho-c-Jun that is suppressed in cells with functional p53 or by forced expression of p21 ( Cip1 )