Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

O'Sullivan et al., J Surg Res 2009 (Inflammation) : The role of P38 MAPK and PKC in BLP induced TNF-alpha release, apoptosis, and NFkappaB activation in THP-1 monocyte cells ... In this study, we set out to examine the precise role of both protein kinase C ( PKC ) and P38 MAPK signaling kinases in bacterial lipoprotein (BLP) induced nuclear factor-kappa B (NFkappaB) activation and tumor necrosis factor-alpha (TNFalpha) release in THP-1 monocytic cell line
Wang et al., J Biol Chem 2002 (MAP Kinase Signaling System) : Pre-exposure of THP-1 cells to BLP suppressed mitogen activated protein kinase phosphorylation and nuclear factor-kappaB activation in response to subsequent BLP and LPS stimulation, which is comparable with that found in LPS tolerized cells, indicating that BLP tolerance and LPS tolerance may share similar intracellular pathways