Gene interactions and pathways from curated databases and text-mining

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ITIH4 — MAPK10

Text-mined interactions from Literome

Kinet et al., Blood 2002 (MAP Kinase Signaling System) : Here, we report that gp120 binding resulted in activation of the mitogen activated protein kinase ( MAPK ) in CD4 ( + ) lymphocytes prestimulated through their T-cell receptor ( TCR ) ... Nevertheless, like peripheral blood lymphocytes, MAPK recruitment was induced by gp120 in UC T cells following TCR prestimulation
Kapasi et al., Mol Med 2002 (MAP Kinase Signaling System) : In addition, gp120 promoted tubular cell p38 MAPK phosphorylation in a time- and dose- dependent manner
Badr et al., J Immunol 2005 (HIV Infections) : Unlike CXCL12, gp120 did not induce the activation of phospholipase Cbeta3 and PI3K downstream from CXCR4, whereas p38 MAPK activation was observed
Bruno et al., Gut 2010 (HIV Infections...) : gp120 also induced activation of nuclear factor-kappaB (NF-kappaB) and p38 ( MAPK )
Kuang et al., Eur J Immunol 2012 (HIV Infections) : Here, we show that NHERF1 can associate with CCR5, and promote activation of the gp120 induced MAPK/ERK , focal adhesion kinase and RhoA ( Ras homolog gene family member A ) signaling pathways