Gene interactions and pathways from curated databases and text-mining

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MET — TCF3

Text-mined interactions from Literome

Boon et al., Cancer Res 2002 (Adenoma...) : Moreover, in CRC cells, induction of dominant negative TCF proteins and the consequent abrogation of beta-catenin/TCF mediated transcriptional activation lead to a strong down-regulation of Met expression
Cherukuri et al., Cancer Biol Ther 2005 (Colorectal Neoplasms) : These results suggest that Se-Met regulates COX-2 at transcriptional level by modulating the activity of NF-kappaB transcription factor
Lim et al., Cancer Res 2008 (Bile Duct Neoplasms...) : Accordingly, DHA treatment also decreased the beta-catenin mediated T cell factor/lymphoid enhancer factor ( TCF/LEF ) reporter activity, and inhibited the expression of c-Met , a beta-catenin controlled downstream gene implicated in cholangiocarcinogenesis
Mascarenhas et al., J Biol Chem 2009 (Adenocarcinoma...) : These data support a model for a neoplastic pathway, where expression of a transcription factor from development activates the MET receptor, a protein that has been directly linked to protumorigenic processes of resisting apoptosis, tumor growth, invasion, and metastasis