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BMP7 — MGP

Text-mined interactions from Literome

Yao et al., Circ Res 2010 (Atherosclerosis...) : To investigate the effect of altered expression of matrix Gla protein (MGP) , an inhibitor of BMP , on vascular disease ... MGP overexpression reduced vascular BMP activity, atherosclerotic lesion size, intimal and medial calcification, and inflammation ... Conversely, MGP deficiency increased BMP activity, which may explain the diffuse calcification of vascular medial cells in MGP deficient aortas and the increase in expression of activin-like kinase receptor 1 and vascular endothelial growth factor
Yao et al., J Clin Invest 2011 (Arteriovenous Malformations...) : Mechanistically, MGP deficiency increased BMP activity in lungs
Haaijman et al., J Bone Miner Res 1997 : OP-1 ( BMP-7 ) affects mRNA expression of type I, II, X collagen, and matrix Gla protein in ossifying long bones in vitro