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IL17A — MMP17

Text-mined interactions from Literome

Koshy et al., Ann Rheum Dis 2002 : IL17 can, alone and synergistically in combination with other proinflammatory cytokines, promote chondrocyte mediated MMP dependent type II collagen release from cartilage
Bamba et al., J Gastroenterol 2003 : In human colonic SEMFs, MMP-3 secretion and MMP-3 mRNA expression were induced by IL-17 , IL-1beta, and TNF-alpha
Sylvester et al., Cell Signal 2004 : ERK pathway inhibitors, PD98059 and U0126, down-regulated IL-17 induced MMP and ADAM-TS4 gene expression
Koenders et al., Arthritis Rheum 2005 (Arthritis, Experimental...) : Moreover, local IL-17 gene transfer increased MMP expression without the need for IL-1, although IL-1 remained essential for part of the cartilage VDIPEN expression
Inatomi et al., Pancreas 2007 : In human pancreatic myofibroblasts, MMP-3 secretion and mRNA expression were induced by interleukin (IL)-17 , IL-1beta, and tumor necrosis factor (TNF) -alpha, respectively
Yagi et al., J Gastroenterol 2007 (Colitis) : IL-17A and IL-17F significantly enhanced IL-6, IL-8, LIF, MMP-1 , and MMP-3 secretion ... Both IL-17A and IL-17F augmented IL-1beta induced secretion of IL-6, IL-8, LIF, MMP-1 , and MMP-3
Agarwal et al., J Rheumatol 2008 (Arthritis, Rheumatoid...) : Increased IL-17 levels in ERA SF correlate with disease activity and this may be due to increased production of MMP and cytokines by IL-17
Wang et al., Cancer Biol Ther 2013 (Bone Neoplasms...) : We observed that IL-17A/IL-17RA interaction promoted the expression of VEGF, MMP9 and CXCR4 in OS cells, which might partly explain the enhanced metastasis of OS cells
Hayata et al., PloS one 2013 (Melanoma, Experimental...) : Inhibition of IL-17A at tumor sites significantly suppressed CD31, MMP9 , and VEGF expression in tumor tissue
Xie et al., PloS one 2013 : Moreover, in cultured cardiac fibroblasts, IL-17A induced the expression of ADAMTS-1, MMP-2 , and collagen subtypes I and III and increased the proliferation of fibroblasts