Gene interactions and pathways from curated databases and text-mining

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AHSA1 — MMP2

Text-mined interactions from Literome

Wang et al., Stem Cells 2005 : Activation of transforming growth factor-beta1/p38/Smad3 signaling in stromal cells requires reactive oxygen species mediated MMP-2 activity during bone marrow damage
Hsieh et al., J Rheumatol 2007 (Osteoarthritis, Knee) : Enzyme linked immunosorbent assay and gelatin zymography were used to investigate the effects of ERK 1/2 inhibitor U0126, JNK and p38 inhibitor SB203580, and PI3K inhibitor LY294002 on the secretion of u-PA, PAI-1, MMP-2 , and MMP-9 in early osteoarthritic tissue cultures, with or without interleukin 1alpha (IL-1alpha) and lipopolysaccharide (LPS) induction
Lin et al., Mol Carcinog 2010 (Nasopharyngeal Neoplasms) : MMP-2 promoter activity and cell invasion were inhibited by p38 mitogen activated protein kinase ( MAPK ) siRNA, inhibitor 4- ( 4-Fluorophenyl ) -2- [ 4- ( methylsulfinyl ) phenyl ] -5- ( 4-pyridyl ) -1H-imidazole ( SB203580 ), and AE, but not by JNK siRNA and inhibitor 1,9-pyrazoloanthrone