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MMP9 — SMAD9
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Kim et al., Invest Ophthalmol Vis Sci 2005
:
To evaluate the effects of TGF-beta1 and doxycycline on production of gelatinase
MMP-9 and
activation of
Smad , c-Jun N-terminal kinase (JNK), extracellular regulated kinase (ERK), and p38 mitogen activated protein kinase ( MAPK ) signaling pathways in human corneal epithelial cells
Xu et al., Angiogenesis 2012
(Choroidal Neovascularization) :
The inhibition of
MMP-9 was
Smad dependent because BMP4 failed to repress TNF induced MMP-9 expression when Smad1,5 was silenced by siRNA