Gene interactions and pathways from curated databases and text-mining

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MMP1 — MSH5

Text-mined interactions from Literome

Lee et al., J Gene Med 2006 (Inflammation...) : Further, alpha-MSH significantly increased matrix metalloproteinase ( MMP ) activity with tissue inhibitors of matrix metalloproteinase ( TIMP ) inactivation
Wang et al., Gene Ther 2006 (Fibrosis...) : Further, alpha-MSH significantly increased matrix metalloproteinase ( MMP ) , while tissue inhibitors of matrix metalloproteinase ( TIMPs ) were inactivated
Kiss et al., Biol Chem Hoppe Seyler 1995 : In order to test the hypothesis whether UV induced alpha-MSH - via a paracrine loop - regulates the synthesis and the activity of collagenase/MMP-1, we studied the effects of alpha-MSH on the expression of MMP-1 and its tissue inhibitor of matrix metalloproteinases ( TIMP-1 ) ... Our data support the view that UV induced alpha-MSH - by the stimulation of collagenase/MMP-1 - may contribute to the loss of interstitial collagen related to cutaneous photoaging