Sonnemann et al., J Cancer Res Clin Oncol 2007
(Sarcoma, Ewing) :
SAHA and NaB induced mitochondrial depolarisation as well as caspase-9 and -3 activities, and their cytotoxic effects could be significantly reduced by the pan-caspase inhibitor z-VAD-fmk
Adnan et al., PloS one 2012
:
In contrast, 10 mM NaB causes significant toxicity in preconfluent cells via apoptosis through caspase-3 activation with reduced GSTA1 activity