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Chakravortty et al., Biochim Biophys Acta 1999
:
In this report, we present the profile of cytokines and adhesion molecules in the cultured and characterized human small intestinal lamina propria fibroblasts in relation to
neutrophil migration and adhesion in
response to
lipopolysaccharide (LPS) extracted from EPEC 055 : B5
Simpson et al., Hum Gene Ther 2001
:
Over-expression of elafin significantly augmented
LPS mediated
neutrophil migration into the airways in vivo ( 1.30 x 10 ( 6 ) neutrophils in BALF after Ad-elafin/LPS treatment, 0.54 x 10 ( 6 ) after Ad-lacZ/LPS ( p < 0.05 ), 0.63 x 10 ( 6 ) after PBS/LPS ( p < 0.05 ) ) and significantly enhanced human neutrophil migration in vitro
Tavares-Murta et al., Inflammation 2001
:
LPS dose-dependently
inhibited the thioglycollate induced
neutrophil migration into the peritoneal cavities ... Our results suggest that NO released by the inducible NO synthase mediates the inhibition of
neutrophil migration mediated by circulating
LPS
Nakamura et al., Proc Natl Acad Sci U S A 2001
:
Studies here demonstrate that elevating Trx levels in circulation either by i.v. injection of recombinant Trx or stimulating Trx release in Trx-transgenic mice dramatically blocks
lipopolysaccharide (LPS) stimulated
neutrophil migration in the murine air pouch chemotaxis model
Maus et al., J Immunol 2003
(Disease Models, Animal...) :
LPS induced
neutrophil migration to the lungs is CCR2 independent
Santos et al., Br J Pharmacol 2003
:
2
LPS ( 5 ng to 10 micro g cavity ( -1 ) ) injected into the 6-day-old pouch
induced a dose- and time dependent
neutrophil migration which peaked between 4 and 6 h, and was maximal following the dose of 100 ng cavity ( -1 ) ( saline : 0.46+/-0.1 ; LPS : 43+/-3.70 x 10 ( 6 ) cells cavity ( -1 ) at 6 h ) ... 4 HOE-140 ( 1 and 2 mg kg ( -1 ) ), a B ( 2 ) receptor antagonist, reduced
LPS induced
neutrophil migration
Sampaio et al., J Leukoc Biol 2004
(Disease Models, Animal...) :
Local pretreatment with BQ-123 or A-127722 ( 150 pmol ), two selective and chemically unrelated endothelin ET ( A ) receptor antagonists, inhibits neutrophil and eosinophil accumulation in
LPS induced pleurisy at 24 h but not
neutrophil migration at 4 h
Renckens et al., J Infect Dis 2006
(Escherichia coli Infections...) :
uPAR ( -/- ) mice demonstrated a decreased
LPS induced
neutrophil migration into peritoneal lavage fluid, whereas the chemokine and cytokine response was unaltered
Reutershan et al., J Clin Invest 2006
:
Critical role of endothelial CXCR2 in
LPS induced
neutrophil migration into the lung
Kukulski et al., J Leukoc Biol 2007
:
Extracellular nucleotides mediate
LPS induced
neutrophil migration in vitro and in vivo ... Here, we demonstrate that these molecules mediate
LPS induced
neutrophil migration in vitro and in vivo ... It is important that in the murine air-pouch model, extracellular nucleotides were instrumental in
LPS induced
neutrophil migration ... Altogether, these data imply that
LPS induces the release of nucleotides from monocytes and that by autocrine stimulation, the latter molecules
regulate neutrophil migration caused by Gram negative bacteria, suggesting a proinflammatory role of extracellular nucleotides in innate immunity
Medeiros et al., Br J Pharmacol 2007
(Edema) :
Both alpha-humulene and trans-caryophyllene inhibit the
LPS induced NF-kappaB activation and
neutrophil migration , although only alpha-humulene had the ability to prevent the production of pro-inflammatory cytokines TNF-alpha and IL-1beta and the in vivo up-regulation of kinin B ( 1 ) receptors
Dal-Secco et al., J Immunol 2008
:
Treatment of mice with H ( 2 ) S synthesis inhibitors, dl-propargylglycine (PAG) or beta-cyanoalanine, reduced
neutrophil migration induced by
LPS or methylated BSA ( mBSA ) into the peritoneal cavity and by mBSA into the femur/tibial joint of immunized mice
Crowe et al., J Immunol 2009
(Acute Lung Injury...) :
Because IL-17A and IL-17F, ligands for IL-17 receptor antagonist (IL-17RA), have been shown to mediate
neutrophil migration into the lung in
response to
LPS or Gram negative bacterial pneumonia, we hypothesized that IL-17RA signaling was critical for acute lung injury in response to pulmonary influenza infection
Kukulski et al., Mol Immunol 2010
(Disease Models, Animal) :
The P2 receptor antagonist PPADS abrogates
LPS induced
neutrophil migration in the murine air pouch via inhibition of MIP-2 and KC production ... In this work, we show that P2 nucleotide receptors control
lipopolysaccharide (LPS) induced
neutrophil migration in the mouse air pouch model ... In addition, the iv administration of a P2 receptor ligand, UTP, enhanced
LPS induced
neutrophil migration ... These data suggest that
LPS induced
neutrophil migration in the air pouch could involve P2Y(4) receptor which is antagonized by PPADS, activated by UTP, but not UDP, and insensitive to suramin
da Silva de Assis et al., Environ Toxicol Pharmacol 2005
:
The number of peritoneal cells and
lipopolysaccharide (LPS) induced
neutrophil migration after exposure was also analyzed
Cunha et al., Eur J Pharmacol 1986
:
It is suggested that inhibition by glucocorticoids of
LPS induced
neutrophil migration in vivo is not due to a direct effect upon the migrating cells but rather to an indirect one, i.e. through blockade of MNCF release by macrophages