◀ Back to ALB
ALB — NOX5
Text-mined interactions from Literome
Higai et al., Clin Chim Acta 2006
:
Amadori modified glycated
albumin predominantly
induces E-selectin expression on human umbilical vein endothelial cells through
NADPH oxidase activation
Whaley-Connell et al., Am J Nephrol 2007
(Albuminuria...) :
We observed time dependent
increases in
NOX activity with bovine serum
albumin ( albumin ) stimulation ( 500 microg/dl, maximum at 20 min, p < 0.05 ) that was inhibited in a concentration dependent manner with the HMG-CoA reductase inhibitor rosuvastatin ( 1 microM, p < 0.05 ) ... Additionally, the Rac1 inhibitor NSC23766 ( 100 ng/ml ) attenuated
albumin activation of
NOX ... These data demonstrate that
albumin mediated
increases in
NOX activity and ROS in PTC are reversed by inhibition of Rac1 signaling with the use of rosuvastatin
Li et al., Biochem Biophys Res Commun 2010
(Diabetic Nephropathies) :
Glycated
albumin activates
NADPH oxidase in rat mesangial cells through up-regulation of p47phox ... Moreover, siRNA mediated knockdown of p47phox inhibited glycated
albumin induced
NADPH oxidase activity and superoxide formation