Gene interactions and pathways from curated databases and text-mining

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NPY — PRKAB2

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Namkoong et al., Diabetes 2005 (Diabetes Mellitus, Experimental...) : Chronic insulin treatment or suppression of hypothalamic AMPK activity completely prevented diabetes induced changes in food intake as well as in hypothalamic AMPK activity and mRNA expression of neuropeptide Y and proopiomelanocortin
Ropelle et al., Diabetes 2008 (Weight Loss) : Leucine and HPD decrease AMPK and increase mTOR activity in the hypothalamus, leading to inhibition of neuropeptide Y and stimulation of pro-opiomelanocortin expression
Verhulst et al., Regul Pept 2012 (Diabetes Mellitus, Experimental) : A role for the energy sensor AMP activated protein kinase (AMPK) and its downstream effector uncoupling protein 2 (UCP2) in the stimulatory effect of exogenous ghrelin on NPY/AgRP expression and food intake has been suggested