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OPN1LW — RELA
Text-mined interactions from Literome
Abraham et al., Crit Care Med 2000
(Respiratory Distress Syndrome, Adult) :
Phosphorylation, ubiquination, and proteolysis of I kappaB allows
NF-kappaB to translocate to the nucleus and
induce transcription, once associated with the transcriptional cofactor
CBP
Ikeda et al., Biochem Biophys Res Commun 2000
:
However, we found that the inhibition by RelA of p53 transcriptional activity is not completely restored by
CBP/p300 overexpression and that a p53 mutant can not
suppress RelA activity despite of its ability to bind CBP/p300
McKay et al., Mol Endocrinol 2000
:
GR-mediated repression of p65 transactivation and p65 mediated repression of GR transactivation, as well as the physical interaction between
NF-kappaB and GR, are
enhanced by
CBP
Zhong et al., Mol Cell 1998
:
Therefore, PKA
regulates the transcriptional activity of
NF-kappa B by modulating its interaction with
CBP/p300