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INS — PC

Text-mined interactions from Literome

Fischer et al., Toxicol Appl Pharmacol 1999 : Potential involvement of calcium, CaM kinase II, and MAP kinases in PCB stimulated insulin release from RINm5F cells ... The presence of extracellular calcium was required for PCB induced insulin release because removal of calcium from the medium attenuated the effect ... In addition, pretreatment of RINm5F cells with the calcium channel blocker verapamil also blocked PCB induced insulin release ... PCB induced insulin release was completely blocked by KN-93 ... The results of the present investigation suggest a role for calcium and CaM kinase II in PCB induced insulin release
Xu et al., Diabetologia 2008 (Insulinoma) : The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta cells