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PDIA3 — STAT3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: PDIA3 — STAT3 (physical association, affinity chromatography technology) Guo et al., J Interferon Cytokine Res 2002*
• IRef Hprd Interaction: PDIA3 — STAT3 (in vitro) Guo et al., J Interferon Cytokine Res 2002*
• IRef Hprd Interaction: PDIA3 — STAT3 (in vivo) Guo et al., J Interferon Cytokine Res 2002*
• IRef Ophid Interaction: STAT3 — PDIA3 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Guo et al., J Interferon Cytokine Res 2002 (Carcinoma, Hepatocellular...) : Likewise, excess exogenous recombinant human GRP58 prepared using a baculovirus expression system preferentially inhibited Stat3 DNA binding activity in the S100 cytosol, suggesting that GRP58 may sequester activated Stat3
Coe et al., J Biol Chem 2010 : We show here that STAT3 dependent signaling is increased in the absence of ERp57 and this can be rescued by expression of ER-targeted ERp57 but not by cytoplasmic targeted protein, indicating that ERp57 affects STAT3 signaling from the lumen of the ER ... ERp57 effects on STAT3 signaling are enhanced by ER luminal complex formation between ERp57 and calreticulin ... In conclusion, we show that ERp57 deficiency in mouse is embryonic lethal at E13.5 and ERp57 dependent modulation of STAT3 signaling may contribute to this phenotype