Gene interactions and pathways from curated databases and text-mining

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PDLIM7 — VEGFA

Text-mined interactions from Literome

Murono et al., Proc Natl Acad Sci U S A 2001 (Nasopharyngeal Neoplasms...) : Finally, we demonstrate that LMP1 increased production of vascular endothelial growth factor ( VEGF ) ... Treatment of LMP1 expressing cells with the COX-2-specific inhibitor ( NS-398 ) dramatically decreased production of VEGF, suggesting that LMP1 induced VEGF production is mediated, at least in part, by COX-2
Yoshizaki et al., Histol Histopathol 2002 (Carcinoma...) : LMP-1 also induces vascular endothelial growth factor through cyclooxygenase-2 activation and interleukin-8 through NF-kappaB activation
Wakisaka et al., Anticancer Res 2003 (Neoplasms) : Production of VEGF , also induced by LMP-1 , is decreased by a COX-2-specific inhibitor
Wakisaka et al., Mol Cell Biol 2004 (Epstein-Barr Virus Infections...) : Moreover, LMP1 induces HIF-1 DNA binding activity and upregulates HRE and VEGF promoter transcriptional activity ... Finally, LMP1 increases the appearance of VEGF protein in extracellular fluids ; induction of VEGF is suppressed by PD98059 or catalase
Wang et al., Eur J Cancer 2010 (Nasopharyngeal Neoplasms...) : LMP1 induces vascular endothelial growth factor ( VEGF ) expression via the JAK/STAT and mitogen activated protein kinase ( MAPK ) /ERK signalling pathways
Chew et al., BMC cancer 2010 (Nasopharyngeal Neoplasms...) : The present study examined the roles of EBV latent membrane protein-1 (LMP1) , interleukin-6 (IL-6), interleukin-10 (IL-10), transforming growth factor-beta 1 ( TGF-ß1 ) and laminin in the regulation of matrix-metalloproteinases ( MMPs ) and vascular endothelial growth factor ( VEGF ) in NPC