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PDLIM7 — VEGFA
Text-mined interactions from Literome
Murono et al., Proc Natl Acad Sci U S A 2001
(Nasopharyngeal Neoplasms...) :
Finally, we demonstrate that
LMP1 increased production of
vascular endothelial growth factor ( VEGF ) ... Treatment of LMP1 expressing cells with the COX-2-specific inhibitor ( NS-398 ) dramatically decreased production of VEGF, suggesting that
LMP1 induced
VEGF production is mediated, at least in part, by COX-2
Yoshizaki et al., Histol Histopathol 2002
(Carcinoma...) :
LMP-1 also
induces vascular endothelial growth factor through cyclooxygenase-2 activation and interleukin-8 through NF-kappaB activation
Wakisaka et al., Anticancer Res 2003
(Neoplasms) :
Production of
VEGF , also
induced by
LMP-1 , is decreased by a COX-2-specific inhibitor
Wakisaka et al., Mol Cell Biol 2004
(Epstein-Barr Virus Infections...) :
Moreover,
LMP1 induces HIF-1 DNA binding activity and
upregulates HRE and
VEGF promoter transcriptional activity ... Finally,
LMP1 increases the appearance of
VEGF protein in extracellular fluids ; induction of VEGF is suppressed by PD98059 or catalase
Wang et al., Eur J Cancer 2010
(Nasopharyngeal Neoplasms...) :
LMP1 induces
vascular endothelial growth factor ( VEGF ) expression via the JAK/STAT and mitogen activated protein kinase ( MAPK ) /ERK signalling pathways
Chew et al., BMC cancer 2010
(Nasopharyngeal Neoplasms...) :
The present study examined the
roles of EBV
latent membrane protein-1 (LMP1) , interleukin-6 (IL-6), interleukin-10 (IL-10), transforming growth factor-beta 1 ( TGF-ß1 ) and laminin in the regulation of matrix-metalloproteinases ( MMPs ) and
vascular endothelial growth factor ( VEGF ) in NPC