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PGP — TNF

Text-mined interactions from Literome

Belliard et al., J Pharm Sci 2004 : The aim of this study was to investigate the effects of TNF alpha and IFN gamma on intestinal Pgp expression, activity, and localization in Caco-2 cells grown on filters ... In conclusion, our results demonstrate an inhibitory effect of TNF alpha and no effect of IFN gamma on Pgp transport activity using rhodamine 123 as a substrate
Pawlik et al., J Pharm Pharmacol 2005 : P-gp inhibitors suppressed the release of IL-2, IL-4, IFN-gamma and TNF-alpha from PHA stimulated MNC, whereas release of IL-6 and IL-10 remained unaffected
Tramonti et al., J Nephrol 2009 (Albuminuria) : TNF-alpha restored Pgp expression and function
Heemskerk et al., J Biomed Biotechnol 2010 : The signaling pathway through which lipopolysaccharide (LPS) or tumor necrosis factor-alpha (TNF-alpha) regulates P-gp expression and activity was investigated further in the present study
Bailly et al., Leukemia 1995 (Leukemia, Myeloid, Acute...) : Recombinant cytokines including GM-CSF, G-CSF, IL-1 beta, IL-6, stem cell factor, LIF, erythropoietin, and IL-3 had no effect on P-gp expression whereas TNF alpha induced dose- and time dependent P-gp and mdr-1 gene overexpression ... However, TNF alpha induced P-gp overexpression had no influence on P-gp efflux capacity