Gene interactions and pathways from curated databases and text-mining

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EPHB2 — PKD1

Text-mined interactions from Literome

Geng et al., Biochem Biophys Res Commun 2009 (Hypertrophy) : In particular, PKD was critical for Ang II-induced ERK5 activation since silencing PKD by siRNA markedly inhibited Ang II-induced ERK5 activation
Chen et al., Carcinogenesis 2011 (Neoplasms, Hormone-Dependent...) : Knockdown of endogenous PKD1 or PKD2 decreased extracellular signal regulated kinase ( ERK ) 1/2 and nuclear factor-kappaB ( NF-?B ) -dependent transcriptional activities and potentiated PMA induced apoptosis, whereas overexpression of wild-type PKD1 enhanced ERK1/2 activity and suppressed PMA induced apoptosis