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MMP19 — PLAT

Text-mined interactions from Literome

Mishiro et al., Neuroscience 2012 (Cerebral Hemorrhage...) : We subjected mice to 6-h filamental middle cerebral artery occlusion ( MCAO ) with vehicle, delayed tPA alone, or combined tPA ( 10 mg/kg, i.v. ) plus GM6001 ( 100 mg/kg, i.p. ), a broad-spectrum MMP inhibitor
Lakhan et al., Frontiers in neurology 2013 : Reactive oxygen species can enhance the effects of tPA on MMP activation through the loss of caveolin-1 ( cav-1 ), a protein encoded in the cav-1 gene that serves as a critical determinant of BBB permeability
Kolben et al., Eur J Obstet Gynecol Reprod Biol 1996 (HELLP Syndrome...) : In HELLP syndrome, tPA and TIMP-1 are also elevated, and in patients with hpD, MMP-8 is increased , whereas MMP-9, and TIMP-1 are lower