Etienne-Manneville et al., J Immunol 2000
(Calcium Signaling) :
Investigating signaling pathways triggered by the engagement of adhesion molecules expressed on brain endothelial cells using two rat brain endothelial cell lines ( RBE4 and GP8 ), we report in this paper that ICAM-1 cross linking induces a sustained tyrosine phosphorylation of the phosphatidylinositol-phospholipase C (PLC)gamma1 , with a concomitant increase in both inositol phosphate production and intracellular calcium concentration
Chang et al., Mol Pharmacol 2004
:
Differential role of Janus family kinases ( JAKs ) in interferon-gamma induced lung epithelial ICAM-1 expression : involving protein interactions between JAKs, phospholipase Cgamma , c-Src, and STAT1