Gene interactions and pathways from curated databases and text-mining

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APP — PLD6

Text-mined interactions from Literome

Lee et al., Neurosci Lett 2001 : The aim of this study was to determine whether overexpression of the amyloid precursor protein (APP) affects the activity and the level of PLD expression in P19 embryonic carcinoma cells ... Although the PKC inhibitor, GF109203X, inhibited PMA stimulated PLD activity, it did not affect the high basal PLD activity induced by APP overexpression ... Interestingly, APP overexpression in the differentiated P19 cells also led to an increase in PLD activity
Jin et al., Neurobiol Aging 2007 (Alzheimer Disease...) : Elevated expression of APP stimulated PLD activity in human astroglioma cells
Singh et al., Neurochem Res 1998 : The activation of phospholipase D by quisqualate and APP ( 25-35 ) was calcium independent