Gene interactions and pathways from curated databases and text-mining

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MUC4 — PPARG

Text-mined interactions from Literome

Slomiany et al., IUBMB Life 2003 (Helicobacter Infections) : Using gastric mucosal cells in culture, we show that activation of PPARgamma with a specific synthetic agonist, ciglitazone, prevents in a dose dependent fashion ( up to 90.2 % ) the LPS induced reduction in mucin synthesis, and the effect is reflected in a marked decrease in the LPS induced apoptosis ( 72.4 % ), NO generation ( 80.1 % ), and the expression of NOS-2 activity ( 90 % )
Slomiany et al., IUBMB Life 2004 : We show that activation of PPARgamma with a specific agonist, ciglitazone, prevents the LPS induced reduction in mucin synthesis, and the effect is reflected in a marked decrease in apoptosis, caspase-3 activity and NO generation
Slomiany et al., Inflammopharmacology 2004 : Using gastric mucosal cells in culture, we show that activation of PPARgamma with a specific agonist, ciglitazone, prevents the LPS induced reduction in mucin synthesis, and the effect is reflected in a marked decrease in apoptosis, caspase-3 activity and NO generation
Lee et al., Am J Physiol Lung Cell Mol Physiol 2006 (Carcinoma, Mucoepidermoid...) : However, no data are available on the role of PPAR-gamma in smoke induced mucin production ... In this study, we investigated the effect of PPAR-gamma agonist ( rosiglitazone ) on smoke induced mucin production in NCI-H292 cells