Gene interactions and pathways from curated databases and text-mining

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PI3 — PPARG

Text-mined interactions from Literome

Patel et al., Curr Biol 2001 : Our results demonstrate a role for PPARgamma in regulating PI 3-kinase signaling by modulating PTEN expression in inflammatory and tumor derived cells
Watanabe et al., Biochem Biophys Res Commun 2003 : Interestingly, PI 3-kinase overexpression resulted in a marked decrease in PPAR gamma activity
Al-Rasheed et al., J Biol Chem 2004 : In addition PI 3-kinase dependent phosphorylation of PPARgamma was observed after stimulation by C-peptide or insulin ... We concluded that insulin and C-peptide can stimulate PPARgamma activity in a ligand independent fashion and that this effect is mediated by PI 3-kinase