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PPP1R12A — RPSA

Text-mined interactions from Literome

Umeda et al., J Biol Chem 2008 (Melanoma, Experimental) : Here we show that ( i ) using a direct genetic screen, eukaryotic translation elongation factor 1A ( eEF1A ) is identified as a component responsible for the anticancer activity of EGCG ; ( ii ) through both eEF1A and 67LR, EGCG induces the dephosphorylation of myosin phosphatase targeting subunit 1 ( MYPT1 ) at Thr-696 and activates myosin phosphatase ; and ( iii ) silencing of 67LR , eEF1A, or MYPT1 in tumor cells results in abrogation of EGCG induced tumor growth inhibition in vivo
Umeda et al., Biochem Biophys Res Commun 2008 (Adenocarcinoma...) : Involvement of 67-kDa laminin receptor mediated myosin phosphatase activation in antiproliferative effect of epigallocatechin-3-O-gallate at a physiological concentration on Caco-2 colon cancer cells