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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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AKT3 — PRDX2

Text-mined interactions from Literome

Chen et al., J Biol Chem 2005 : However, the effect of TSA on phospho-Akt can be rescued by PP1 inhibition but not that of protein phosphatase 2A
Zhou et al., Int J Oncol 2006 (Ovarian Neoplasms) : Accumulated experimental data indicate that TSA activates phosphatidyl inositol-3-kinase (PI3K)/AKT signaling ... TSA transiently activated EGFR tyrosine phosphorylation and AKT activation in a time- and dose dependent manner, which had been inhibited by EGFR inhibitor PD153035 and PI3 kinase inhibitor LY294002
Emonds et al., World J Gastroenterol 2010 (Pancreatic Neoplasms) : In BxPC-3 cells ( which are wild-type for KRAS ), TSA strongly inhibited phosphorylation of ERK 1/2 and AKT
Shi et al., Biochem Biophys Res Commun 2013 : In parallel, hypoxia and TSA synergistically increased p-ERK and p-Akt without effecting VEGF-A level