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GNRH1 — PRKACB

Text-mined interactions from Literome

Vitalis et al., Proc Natl Acad Sci U S A 2000 : In fact, pharmacological inhibition of PKA activity caused an increase in the basal secretion of GnRH
Chiang et al., J Clin Endocrinol Metab 2000 : Furthermore, our data suggest that the effects of hCG and GnRH on ERalpha and ERbeta expression in hGLCs are mediated in part by activation of PKA and PKC signaling pathways, respectively
Ferris et al., Biol Reprod 2007 : In LbetaT2 cells, cAMP stimulation of the Lhb promoter was eliminated by inhibition of protein kinase A (PKA) ; GnRH1 stimulation was partially suppressed by either PKA or protein kinase C inhibitors ... Thus, cAMP stimulation of Lhb promoter activity, and enhancement of GnRH1 stimulation, occurs in multiple physiological states independent of steroid status, via a PKA dependent mechanism
Dhillon et al., Regul Pept 2009 : Pharmacological inhibitors of the MAPK and PKA signal transduction pathways attenuated the NPY mediated increase in GnRH transcription
Thompson et al., Mol Endocrinol 2013 : GnRH stimulation of CREB phosphorylation ( pCREB ) in the gonadotrope derived LßT2 cell line was attenuated by a protein kinase A (PKA) inhibitor, H89
Lei et al., Mol Cell Endocrinol 1995 : Treatment with the PKA inhibitor alone modestly decreased GnRH mRNA levels suggesting that PKA signaling also controls the basal expression of the GnRH gene