Tschäpe et al., EMBO J 2002
:
Although Drosophila can not synthesize cholesterol de novo, the regulatory role of fly AMPK on HMG-CoA reductase is conserved
Oliaro-Bosso et al., Lipids 2009
:
Beneficial effects of policosanol in the prevention of atherosclerosis and thromboembolic disorders have been reported and related to the inhibition of sterol biosynthesis possibly by the regulation of the activity of HMGCoA reductase mediated by AMP dependent kinase AMPK