Gene interactions and pathways from curated databases and text-mining

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LPA — PRKAR2B

Text-mined interactions from Literome

Nguyen et al., Cell Signal 2004 (Carcinoma, Hepatocellular...) : These results suggest that PKA inhibits LPA stimulation of SRF by promoting the dissolution of F-actin and that this is likely to contribute to the cAMP mediated inhibition of ovarian cancer cell growth
Hirakawa et al., J Pharmacol Exp Ther 2007 : These results indicate that LPA induces cAMP/PKA-sensitive , RhoA mediated random migration of BTSMCs. Regulation of this mechanism would be beneficial for the control of airway remodeling