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CCK — PRL

Text-mined interactions from Literome

Tanimoto et al., Endocrinology 1987 : Proglumide ( 0.2 mg/kg, iv ) and benzotript ( 0.2 mg/kg, iv ), specific CCK receptor antagonists, blocked the icv CCK-8 induced increase in plasma PRL levels ... There was no apparent effect of icv CCK-8 on the enhancement of PRL release by haloperidol ( 0.2 mg/kg, iv ), sulpiride ( 0.1 mg/kg, iv ), domperidone ( 0.1 mg/kg, iv ), or RO22-1319 ( 0.1 mg/kg, iv ) ... Furthermore, icv CCK-8 increased plasma PRL levels in rats depleted of dopamine by pretreatment with reserpine and alpha-methyl-p-tyrosine
Vijayan et al., Life Sci 1987 : These results indicate that proglumide can lower prolactin in male rats and suggests a physiologically significant role of CCK in the control of prolactin secretion in the male
Matsumura et al., Horm Metab Res 1985 : Intravenous injection of 5 micrograms/100 g BW of CCK-8 resulted in significant increase in the plasma PRL level after 10 and 20 min. CCK-8 at concentrations of 10 ( -11 ) M to 10 ( -7 ) M also caused dose dependent stimulation of PRL release from dispersed cells of rat anterior pituitary ... Addition of 10 ( -3 ) M verapamil to the incubation medium inhibited CCK-8 induced PRL release from the cells
Karashima et al., Endocrinol Jpn 1984 : Suppressive effects of cholecystokinin and bombesin on growth hormone and prolactin secretion in urethane anesthetized rats ... The effects of cholecystokinin octapeptide (CCK) and bombesin on rat plasma growth hormone (GH) and prolactin (PRL) levels were investigated with the animals under urethane anesthesia ... These results indicate that the CCK and bombesin act much in the same manner to inhibit GH and PRL
Lal et al., Prog Neuropsychopharmacol Biol Psychiatry 1983 (Synaptic Transmission) : CCK-33 ( 225 Ivy Dog Units iv ) antagonized the growth hormone response to the dopamine receptor agonist, apomorphine HCl ( 0.5 mg sc ), and increased basal prolactin secretion in normal male volunteers
Nair et al., Neuropeptides 1984 : CCK-33 antagonizes apomorphine induced growth hormone secretion and increases basal prolactin levels in man ... Cholecystokinin ( CCK-33 ) ( 225 Ivy Dog Units intravenously ) had no effect on basal growth hormone (GH) secretion but antagonized the GH response to the dopamine receptor agonist, apomorphine HCl ( 0.5 mg sc ) ( N = 7 ), and induced a transient increase in basal prolactin (PRL) secretion ( N = 8 ) in normal men ... However, an inhibitory effect of CCK-33 on the release of GH and a stress induced increase in PRL secretion can not be excluded
Zhou et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1995 : [ Effect of cholecystokinin on prolactin release and its action mechanism in the rats ]