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AKT2 — PSMD10

Text-mined interactions from Literome

Smith et al., Am J Physiol Endocrinol Metab 2008 (Sepsis...) : Other important consequences of calpain activation that may contribute to muscle wasting during sepsis include degradation of certain transcription factors and nuclear cofactors, activation of the 26S proteasome , and inhibition of Akt activity, allowing for downstream activation of Foxo transcription factors and GSK-3beta
Man et al., J Clin Invest 2010 (Cell Transformation, Neoplastic...) : In addition, we found that Gankyrin is highly expressed in human lung cancers that have Ras mutations and that increased Gankyrin expression is required for the constitutive activation of Akt and tumorigenesis in these lung cancers
Fu et al., Hepatology 2011 (Carcinoma, Hepatocellular...) : The p28(GANK) activates phosphoinositide 3-kinase (PI3K)-V-akt Murine Thymoma Viral Oncogene Homolog ( AKT ) -hypoxia-inducible factor 1a (HIF-1a) signaling to promote TWIST1, vascular endothelial growth factor, and metalloproteinase 2 expression