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RAB14 — RASA1
Text-mined interactions from Literome
Sadacca et al., Mol Biol Cell 2013
:
Although both RAB10 and
RAB14 are
regulated by the
GAP activity of AS160 in vitro, only RAB10 is under the control of AS160 in vivo
Seabra et al., J Biol Chem 1996
:
In vitro REP.Rab binding assays demonstrate that REP forms a stable complex only with the GDP bound form of Rab but not the GTP bound form, suggesting that the apparent Km effect in the prenylation reaction is due to a discrimination between the two different nucleotide bound forms of Rab by REP. Inasmuch as Rabs are likely GTP bound after synthesis and REP does not possess GTPase activating protein activity, these results raise the possibility that a Rab
GTPase activating protein enhances the
REP*Rab interaction prior to prenylation