Gene interactions and pathways from curated databases and text-mining

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ANGPT1 — RAC1

Text-mined interactions from Literome

David et al., Arterioscler Thromb Vasc Biol 2011 : Angiopoietin-1 requires IQ domain GTPase activating protein 1 to activate Rac1 and promote endothelial barrier defense
Oubaha et al., Blood 2012 : This complex brings Par3, Par6, and adherens junction proteins at the front of migrating cells to locally activate Rac1 in response to Ang-1