Gene interactions and pathways from curated databases and text-mining

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HGF — RAF1

Text-mined interactions from Literome

Taniguchi et al., Mol Reprod Dev 2004 (MAP Kinase Signaling System) : Here, we showed that HGF activated the distinct phosphorylation of Raf-1 , MEK1/2, and ERK1/2, but did not induce phosphorylation of Akt
Rush et al., Exp Cell Res 2007 (MAP Kinase Signaling System) : Stimulation of HBMECs by HGF led to rapid activation of ERK1/2, phosphorylation of Raf-1 at Ser ( 338 ) and Tyr ( 340/341 ) and MEK1/2 at Ser ( 222 )
Tanimura et al., Oncogene 1998 : AMPC-pretreatment, however, did not affect HGF-, PMA- or EGF induced activation of Raf-1 , nor HGF induced activation of phosphatidylinositol 3-kinase in these cells