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RBM38 — TP53
Text-mined interactions from Literome
Zhang et al., Genes Dev 2011
(Lymphoma) :
Translational
repression of
p53 by
RNPC1 , a p53 target overexpressed in lymphomas ... Importantly, we showed that
RNPC1 inhibits ectopic expression of
p53 in a dose dependent manner via p53 5 ' or 3 ' UTR ... Moreover, we showed that loss of
RNPC1 in mouse embryonic fibroblasts
increased the level of
p53 protein, leading to enhanced premature senescence in a p53 dependent manner
Léveillé et al., Nature communications 2011
:
RBM38 is
induced by
p53 and its ability to modulate miRNA mediated repression is required for proper p53 function